Joint Injections in Dallas
PRP & Prolozone: Non-Steroid Injection Options
In-office PRP and Prolozone injections for knee, shoulder, hip and tendon pain, given by a licensed provider after an evaluation at our East Dallas clinic.
What Joint Injections Do We Offer?
Regen Wellness offers two non-steroid joint injections in Dallas: PRP (platelet-rich plasma), made from a small sample of your own blood, and Prolozone, a numbing and nutrient solution followed by medical-grade ozone. Both are injected into or around a painful knee, shoulder, hip, elbow, ankle or the soft tissue along the spine.
Every injection is given by a licensed provider after an evaluation at our East Dallas clinic. Neither PRP nor Prolozone is FDA-approved to treat joint conditions, and we explain what the research does and doesn't show before you decide.
Not sure an injection is the right next step? See how we evaluate joint pain.
PRP vs. Prolozone at a Glance
Both are in-office injections aimed at one painful area. They differ in what's injected, how the visit runs and how much research is behind them. Your provider will explain which, if either, fits your pain.
| PRP | Prolozone | |
|---|---|---|
| What's injected | Platelet-rich plasma concentrated from your own blood | Procaine, dextrose and vitamins, followed by ozone and oxygen gas |
| The idea behind it | Concentrated platelets release growth factors in the treated area | Combines prolotherapy's approach with ozone, which is studied for its effects on inflammation |
| The visit | A blood draw, then the PRP is prepared and injected at the same visit | The solution and ozone are injected at one visit, with no blood draw |
| Your plan | How many injections you have, and how far apart, is personalized to your pain, how you respond and your goals. | |
| What the evidence shows | Mixed. Some knee arthritis trials show pain relief lasting months, others show little difference from placebo, and preparations vary. | Ozone injections for knee arthritis reduced pain more than placebo in trials, mostly in the first 1–2 months. Evidence quality is rated low. |
| FDA status | Prepared with FDA-cleared devices, but not FDA-approved to treat joint conditions | FDA has not approved ozone for any medical use |
Want the full detail on Prolozone, including how the technique was developed and its own safety notes? See our Prolozone therapy page. The rest of this page focuses on PRP and what both injections have in common.
See Joint Injection Pricing
Get our pricing sheet for PRP and Prolozone emailed to you, with no obligation. Prefer to talk it through first? Book a free info call.
What to Expect at a PRP Injection Visit
Free info call
Tell us where it hurts and what you've tried. We'll explain whether PRP or Prolozone might fit, what the visit involves and the cost, with no obligation.
Provider evaluation
A licensed provider examines the area and reviews your symptoms, history, medications and any imaging you bring. If an X-ray, MRI or specialist opinion makes sense first, we'll tell you.
Blood draw and preparation
A small amount of your blood is drawn from the arm, the same way as for lab work. It's spun in a centrifuge to separate and concentrate the platelets.
Your injection
The skin is cleaned and numbed, and the PRP is injected into the joint or around the tendon. Your provider chooses the injection site based on your exam, your symptoms and any imaging you've provided. How long your visit takes depends on how many areas are treated and how many injections you need.
The next few days
Soreness and swelling for a few days are common. Your provider will tell you which pain relievers to use, since anti-inflammatory medicines are usually paused around PRP, and when to return to exercise.
Your personalized plan
Any change usually builds gradually over several weeks rather than right away. Your provider checks how you're responding and plans any further injections around your pain and your goals.
What Does the Research on PRP Show?
PRP has been studied more than most injection options, but results differ between trials, partly because there's no single standard way to prepare it. Here's the published evidence in plain terms.
| Area | What has been studied | Human evidence |
|---|---|---|
| Knee osteoarthritis | PRP injected into the knee, compared with saline (placebo) or hyaluronic acid | The most-studied use. Several trials and meta-analyses found less pain and better function at 6–12 months. A large 2021 randomized trial in Australia found no difference from saline at 12 months. Results vary with the preparation and how advanced the arthritis is. |
| Tennis and golfer's elbow | PRP injected around the elbow tendons | Mixed. Some trials favor PRP over the comparison, while others found little difference from placebo. |
| Shoulder tendon pain | PRP injected around the rotator cuff tendons | Small trials with mixed results. |
| Hip osteoarthritis | PRP injected into the hip joint | Fewer and smaller trials. So far PRP hasn't clearly outperformed other injections. |
PRP is not FDA-approved to treat any joint condition. We present it as one option for joint and tendon pain, explain the evidence and its limits, and don't promise results.
Who Considers Joint Injections, and Who Shouldn't
Patients usually ask about PRP or Prolozone for pain in one area that has lasted months, especially after rest and physical therapy haven't helped enough, or when they want a non-steroid option. Injections work best alongside strengthening, not instead of it.
- Not a fit: pregnancy, an infection in or near the area to be treated, a fever or active infection elsewhere, or a cancer affecting the blood or bone.
- Tell us first if you take blood thinners, have a bleeding disorder, low platelets or anemia, or have had another injection into the same area recently.
- Tell us about pain relievers. Anti-inflammatory medicines such as ibuprofen and naproxen may need to be paused before and after PRP. Don't stop a prescribed medicine without talking to your provider.
- Get checked first if your pain came from a recent injury, comes with swelling, redness, fever, numbness or weakness, or wakes you at night. These need a diagnosis before any injection.
Evaluation First
No one receives an injection without a provider visit. We review your symptoms and history, examine the painful area and look at any imaging you already have, so bring any X-ray or MRI reports. Some patients also need lab work before their first injection.
Are PRP Injections Safe? Side Effects and Risks
Because PRP comes from your own blood, allergic reactions are unlikely. In published trials, side effects were mostly mild and short-lived. Any injection still carries risks:
- Common and short-lived: soreness, stiffness and swelling in the treated area for a few days, and bruising at the injection or blood-draw site.
- Less common: a pain flare lasting longer than a few days, and lightheadedness or fainting during the blood draw or injection.
- Rare but serious: infection in the joint or tissue, and nerve or blood vessel injury. Sterile technique and careful placement reduce these risks.
Prolozone's side effects are covered on the Prolozone page. After either injection, call us right away, or seek urgent care, if you develop fever, spreading redness or warmth, or pain that keeps getting worse after day 3.
Who Provides Your Joint Injections
Injections are given by a licensed provider after an evaluation, working with our clinic director, Jose Baldazo, BSN, RN. Our team trained in Prolozone under Dr. Frank Shallenberger, MD, who developed the technique.
All injection protocols are overseen by our medical director, Dr. Adam Parsons, MD, who completed a fellowship in sports medicine and interventional pain management. We work alongside your physical therapist, primary care doctor and any specialists you see.
Medically Reviewed
Reviewed by Jose Baldazo, BSN, RN, Clinic Director, and approved by Dr. Adam Parsons, MD, Medical Director.
Last reviewed: October 2026.
Related Care at Our Dallas Clinic
Joint Pain
How we evaluate knee, shoulder, hip and back pain, and the full plan around any injection.
Joint pain care →Prolozone Therapy
Our ozone-based injection, the technique behind it, the research and what to expect.
Prolozone →Athletic Performance & Recovery
Recovery support for runners, lifters and active adults.
Performance & recovery →BPC-157
A peptide some patients ask about for recovery, prescribed after a provider visit.
BPC-157 →Ozone Therapy Overview
Every ozone option we offer, including IV ozone and insufflation, compared side by side.
All ozone therapies →Lab Testing
Inflammation, vitamin D and other markers that can affect pain and recovery.
Lab testing →Joint Injection FAQs
What is a PRP injection?
PRP stands for platelet-rich plasma. A small amount of your blood is drawn and spun in a centrifuge to concentrate the platelets, which carry growth factors. That concentrate is then injected into a painful joint or around a tendon. Because it comes from your own blood, nothing foreign is injected.
What's the difference between PRP and Prolozone?
PRP uses your own concentrated platelets and needs a blood draw. Prolozone uses a numbing and nutrient solution followed by medical ozone, with no blood draw. PRP has more published trials. Your provider can help you decide which fits. Learn more about Prolozone.
Are your joint injections steroid shots?
No. PRP and Prolozone are both non-steroid injections, and many patients come to us looking for a non-steroid option. PRP research is mixed, and Prolozone has shown pain relief in knee arthritis trials, mostly in the first one to two months, with low-quality evidence overall.
Do PRP injections hurt?
The blood draw feels like any routine lab draw. The injection site is numbed, but many people feel pressure and some discomfort as the PRP goes in. Soreness and swelling for a few days afterward are common.
How many PRP injections will I need?
There's no set number. How many injections you have, and how far apart, is personalized to your pain, how you respond and your goals. Your provider checks your progress before recommending another. Some people don't respond, and if that's the case we'll say so.
How long does PRP take to work?
PRP isn't a quick fix. When it helps, any change usually builds gradually over several weeks. In knee arthritis trials that found a benefit, it was measured at around 6 to 12 months.
Can I take ibuprofen after a PRP injection?
Anti-inflammatory pain relievers such as ibuprofen and naproxen are usually paused for a period before and after PRP, because they may affect how platelets work. Your provider will tell you how long and what you can take for discomfort instead.
Is PRP FDA-approved?
The devices used to prepare PRP are FDA-cleared, but PRP injections aren't FDA-approved to treat joint conditions. Prolozone isn't FDA-approved either. Both are offered in integrative and sports medicine, and we explain the evidence and its limits before you decide.
Does insurance cover joint injections?
PRP and Prolozone usually aren't covered, because they aren't standard insurance-covered treatments. Our services are self-pay, and many patients use HSA or FSA funds. Check with your plan administrator.
How much do joint injections cost in Dallas?
Cost depends on whether you choose PRP or Prolozone, the area treated and your personalized plan. Your first call is free, and you'll get a clear price before you commit. Request our pricing sheet.
Where can I get PRP injections in Dallas?
At Regen Wellness, 5510 Abrams Rd, Suite 126, Dallas, TX 75214, in East Dallas near Lakewood and White Rock Lake. Patients come from across Dallas. See all areas we serve.
Get Joint Injection Pricing
See what PRP and Prolozone cost at our Dallas clinic, or book a free info call to talk through whether either fits your pain.
This page is educational and is not medical advice. PRP and Prolozone are not FDA-approved to treat joint conditions, and FDA has not approved ozone for any medical use. Treatment requires an evaluation by a licensed provider, and individual results vary.