IV Ozone Therapy in Dallas
IV Ozone Therapy by Certified Medical Ozone Specialists
Standard MAH and 10-pass ozone, given by a nurse trained under Dr. Frank Shallenberger, with screening labs first.
What Is IV Ozone Therapy?
IV ozone therapy, also called major autohemotherapy (MAH), is a treatment in which a measured amount of your blood is drawn into a sterile container, mixed with a precise dose of medical-grade ozone and oxygen, and returned to you through the same IV line. It is used in integrative medicine to support circulation, oxygen use and the body's natural defenses. It is not FDA-approved for any medical condition.
At Regen Wellness in Dallas, we offer standard MAH, 10-pass ozone and O3UV (ozone plus ultraviolet light), given by a nurse trained in medical ozone under Dr. Frank Shallenberger and overseen by our medical director.
IV Ozone Options at Our Dallas Clinic
Standard MAH
One cycle: a measured amount of blood is ozonated and returned through the IV. This is the most common and most studied way to give ozone by IV, and where most patients start.
Session length: about 45–60 minutes.
10-Pass Ozone
A higher-intensity version of MAH. The same draw-ozonate-return cycle is repeated, up to 10 times in a single visit, so more blood is treated with ozone in one session.
Session length: about 1.5–2 hours. Usually considered after you've tolerated standard MAH.
O3UV (Ozone + UV Light)
MAH with an added step: before your ozonated blood is returned, it passes through a sterile line exposed to ultraviolet (UV) light. This is also called ultraviolet blood irradiation (UBI or UVBI) combined with ozone.
Session length: about 60 minutes.
What We Don't Do
We never inject ozone gas directly into a vein. Direct IV gas injection carries a risk of gas bubbles in the bloodstream (embolism). With MAH, ozone mixes with your blood outside the body before it is returned.
See IV Ozone Pricing
Get our pricing sheet for standard MAH, 10-pass and O3UV emailed to you, with no obligation. Prefer to talk it through first? Book a free info call.
What Does the Research on Ozone Therapy Show?
Medical ozone has been used for decades, mostly in Europe and Latin America, and is studied by groups such as the International Scientific Committee of Ozone Therapy. Most research is laboratory work, animal studies and small human trials. The strongest human evidence is for ozone injections into joints and spinal discs, not for IV ozone. Learn about our ozone joint injections on the Prolozone therapy page.
| Area | What has been studied | Human evidence |
|---|---|---|
| Oxygen use & circulation | Effects of ozonated blood on red blood cells, oxygen delivery and blood flow | Lab studies and small human studies |
| Immune & antioxidant response | Low, controlled doses of ozone triggering the body's own antioxidant and immune signaling | Mostly lab and animal research, with small clinical studies |
| Joint & back pain | Ozone injected into knees and spinal discs | Randomized trials exist for knee osteoarthritis and disc herniation. These use injections, not IV ozone. |
| UV blood irradiation (the “UV” in O3UV) | Exposing a small amount of blood to UV light, a practice dating back to the 1930s and 1940s, studied for immune and circulation effects | Mostly older studies and small modern trials. Limited evidence, and not FDA-approved for any condition. |
| Chronic fatigue, infections & other uses | Wide range of conditions in case reports and small trials | Limited and mixed. Not enough to say IV ozone treats any of them. |
In the United States, FDA has not approved ozone for any medical use. We present IV ozone as a supportive therapy, explain the evidence plainly, and use it alongside, never instead of, standard medical care.
Who Considers IV Ozone, and Who Shouldn't
Patients usually ask us about IV ozone as part of a broader plan for energy, recovery, healthy aging or immune support. Whether it fits depends on your history, labs and medications.
Active or training for an event? See our athletic recovery and performance care.
- Do not have IV ozone if you have G6PD deficiency, an inherited enzyme condition that makes red blood cells vulnerable to oxidative stress. We screen for it before your first session.
- Also not a fit: pregnancy, uncontrolled overactive thyroid, bleeding disorders or very low platelets, recent heart attack or stroke, and active internal bleeding.
- For O3UV, also tell us if you take medications that make you sensitive to sunlight (some antibiotics, acne and psoriasis medications, among others) or have a light-sensitivity condition such as porphyria or lupus.
- Tell us about every medication, especially blood thinners, and any history of heparin allergy or low platelets after heparin (HIT), and about any history of seizures or anemia.
Screening First
Before your first IV ozone session, we review your health history and order labs, including a complete blood count (CBC) and a G6PD test, if you don't already have recent results.
What to Expect at Your IV Ozone Session
Free info call
Tell us your goals. We'll explain the options, the screening you need and the cost, with no obligation.
Provider visit and screening labs
A provider reviews your history and medications and orders screening labs, including a CBC and G6PD.
Your session
You relax in a comfortable chair. A nurse places an IV, draws a measured amount of blood into a sterile medical-grade container, mixes it with a precise ozone dose and returns it through the same line. With O3UV, the blood also passes through a UV light chamber on its way back. A small amount of heparin, a standard blood thinner, keeps the blood from clotting during the process.
After your session
Most people return to normal activities the same day. Some feel energized, others feel tired for the rest of the day. Drink water and eat a normal meal. Read more in what to expect during a medical ozone session.
Follow-up
Your provider recommends how many sessions to try and how often, then checks in to see how you're responding before you continue.
Is IV Ozone Safe? Side Effects and Risks
When given by trained staff with proper screening, MAH is generally well tolerated in published reports. It still carries risks you should know about:
- Common, short-lived effects: bruising or soreness at the IV site, lightheadedness, tiredness or a mild flu-like feeling after the session.
- Less common: fainting during the blood draw, vein irritation and allergic reactions to heparin.
- Serious but rare: breakdown of red blood cells in people with undiagnosed G6PD deficiency, which is why we test first, and gas embolism, which is linked to direct IV gas injection, a method we don't use.
- Ozone is never breathed into the lungs. Breathing ozone irritates the airways. All ozone is handled in closed, sealed equipment.
Myths and real risks are covered in 4 myths about ozone therapy, debunked.
Who Provides Your IV Ozone
IV ozone at Regen Wellness is given by our clinic director, Jose Baldazo, BSN, RN, who trained in medical ozone therapy under Dr. Frank Shallenberger, MD. Before nursing, Jose worked as a firefighter and paramedic.
All ozone protocols are overseen by our medical director, Dr. Adam Parsons, MD. No one receives IV ozone without a provider visit, screening labs and a clear explanation of risks and alternatives.
Medically Reviewed
Reviewed by Jose Baldazo, BSN, RN, Clinic Director, and approved by Dr. Adam Parsons, MD, Medical Director.
Last reviewed: October 2026.
Related Care at Our Dallas Clinic
Ozone Therapy Overview
Every ozone option we offer, including insufflation, compared side by side.
All ozone therapies →NAD+ Therapy
IV and injection options, often paired with ozone in healthy-aging plans.
NAD+ therapy →Hydrogen Peroxide IV
Another oxidative therapy some patients ask about alongside ozone.
Hydrogen peroxide IV →Longevity Program
A structured plan for healthy aging built on labs, lifestyle and targeted therapies.
Longevity program →IV Ozone Therapy FAQs
Is IV ozone therapy safe?
When given as MAH by trained staff, after screening for G6PD deficiency and other conditions, it is generally well tolerated in published reports. Side effects are usually mild, such as bruising, tiredness or lightheadedness. It isn't right for everyone, which is why every patient sees a provider first.
Is ozone therapy FDA-approved?
No. FDA has not approved ozone for any medical condition. IV ozone is offered in integrative medicine as a supportive therapy, and we explain the evidence and its limits before you decide.
What's the difference between MAH and 10-pass ozone?
Standard MAH treats one measured amount of blood with ozone and returns it, in about 45–60 minutes. 10-pass repeats that cycle up to 10 times in one visit, so it takes longer and is more intensive. Most patients start with standard MAH.
What is O3UV therapy?
O3UV combines IV ozone (MAH) with ultraviolet blood irradiation. Your blood is mixed with ozone, then passes through UV light before it's returned through the IV. It's not FDA-approved for any condition, and research is limited. Your provider will explain whether it fits your goals and check your medications for light sensitivity first.
Does IV ozone hurt?
You'll feel the IV needle going in, like a blood draw. After that, most people find the session comfortable. Some feel a brief coolness or pressure in the arm as blood is returned.
How do people feel after an ozone session?
It varies. Some people feel more energetic, and some feel tired or slightly achy for the rest of the day. Most return to normal activities the same day.
How many IV ozone sessions will I need?
There's no standard number. Your provider recommends a short initial series based on your goals, then reviews how you're responding before suggesting more.
Is this the same as direct IV ozone injection?
No. Direct injection of ozone gas into a vein carries a risk of gas embolism, and we don't offer it. With MAH, ozone mixes with your blood outside your body first.
How much does IV ozone therapy cost?
Cost depends on whether you choose standard MAH, 10-pass or O3UV and how many sessions you need. Your first call is free, and you'll get a clear price before you commit. Our services are self-pay, and many patients use HSA or FSA funds. Request our pricing sheet.
Where can I get IV ozone therapy in Dallas?
At Regen Wellness, 5510 Abrams Rd, Suite 126, Dallas, TX 75214, in East Dallas near Lakewood and White Rock Lake. Patients come from across Dallas. See all areas we serve.
Get IV Ozone Pricing
See what standard MAH, 10-pass and O3UV cost at our Dallas clinic, or book a free info call to talk through which option fits you.
This page is educational and is not medical advice. Ozone therapy and ultraviolet blood irradiation are not FDA-approved for any medical condition. Treatment requires a consultation with a licensed provider, and individual results vary.